Publications

1. Li X, Fan H, Song X, Song B, Liu W, Dong R, Zhang H, Guo S, Liang H, Schrodi SJ  et al.  DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy.  Epigenetics  2023 Dec;18(1):2195307. pii:2195307
2. Pang L, Dunterman M, Guo S, Khan F, Liu Y, Taefi E, Bahrami A, Geula C, Hsu WH, Horbinski C  et al.  Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma.  Nat Immunol  2023 Oct;24(10):1654-1670. doi:10.1038/s41590-023-01605-y
3. Upadhyay A, Chhangani D, Rao NR, Kofler J, Vassar R, Rincon-Limas DE, Savas JN  Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity.  Mol Neurodegener  2023 Sep 14;18(1):61. pii:61
4. Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE  et al.  Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.  Cell Genom  2023 Sep 13;3(9):100399. pii:100399
5. Cho H, Mundada NS, Apostolova LG, Carrillo MC, Shankar R, Amuiri AN, Zeltzer E, Windon CC, Soleimani-Meigooni DN, Tanner JA  et al.  Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS).  Alzheimers Dement  2023 Sep 10;. doi:10.1002/alz.13453
6. Bonakdarpour B, Zhou G, Huang D, Vidano CT, Schuele S, Zelano C, Takarabe C  Calming effect of Clinically Designed Improvisatory Music for patients admitted to the epilepsy monitoring unit during the COVID-19 pandemic: a pilot study.  Front Neurol  2023;14:1206171. pii:1206171
7. Kosche C, Jaishankar D, Cosgrove C, Ramesh P, Hong S, Li L, Shivde RS, Bhuva D, White BEP, Munir SS  et al.  Skin Infiltrate Composition as a Telling Measure of Responses to Checkpoint Inhibitors.  JID Innov  2023 Sep;3(5):100190. pii:100190
8. Celis K, Moreno MDMM, Rajabli F, Whitehead P, Hamilton-Nelson K, Dykxhoorn DM, Nuytemans K, Wang L, Flanagan M, Weintraub S  et al.  Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk.  Alzheimers Dement  2023 Sep;19(9):3902-3915. doi:10.1002/alz.13075
9. Nassan M, Daghlas I, Piras IS, Rogalski E, Reus LM, Pijnenburg Y, Cuddy LK, Saxena R, Mesulam MM, Huentelman M  Evaluating the association between genetically proxied ACE inhibition and dementias.  Alzheimers Dement  2023 Sep;19(9):3894-3901. doi:10.1002/alz.13062
10. Bushnell J, Hammers DB, Aisen P, Dage JL, Eloyan A, Foroud T, Grinberg LT, Iaccarino L, Jack CR, Kirby K  et al.  Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.  Alzheimers Dement  2023 Aug 31;. doi:10.1002/alz.13434
11. Gasca-Salas C, Duff-Canning S, McArthur E, Armstrong MJ, Fox S, Meaney CA, Tang-Wai DF, Gill D, Eslinger PJ, Zadikoff C  et al.  Predictors of Cognitive Change in Parkinson Disease: A 2-year Follow-up Study.  Alzheimer Dis Assoc Disord  2023 Aug 22;. doi:10.1097/WAD.0000000000000576
12. Echevarria-Cooper SL, Ho EH, Gershon RC, Weintraub S, Kahnt T  Evaluation of the NIH Toolbox Odor Identification Test across normal cognition, amnestic mild cognitive impairment, and dementia due to Alzheimer's disease.  Alzheimers Dement  2023 Aug 21;. doi:10.1002/alz.13426
13. Minogue G, Kawles A, Zouridakis A, Keszycki R, Macomber A, Lubbat V, Gill N, Mao Q, Flanagan ME, Zhang H  et al.  Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with Transactive Response DNA-binding Protein 43.  Ann Neurol  2023 Aug 18;. doi:10.1002/ana.26762
14. Mao C, Xu J, Rasmussen L, Li Y, Adekkanattu P, Pacheco J, Bonakdarpour B, Vassar R, Shen L, Jiang G  et al.  AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease.  J Biomed Inform  2023 Aug;144:104442. doi:10.1016/j.jbi.2023.104442
15. Hosseini O, Wang J, Lee O, Pulliam N, Mohamed A, Shidfar A, Chatterton RT, Blanco L, Meindl A, Helenowski I  et al.  ASO Visual Abstract: Menstrual Phase and Menopausal Status Classification of Benign Breast Tissue Using Hormone-Regulated Gene Expression and Histomorphology: A Validation Study.  Ann Surg Oncol  2023 Aug;30(8):5225-5226. doi:10.1245/s10434-023-13389-4
16. Hosseini O, Wang J, Lee O, Pulliam N, Mohamed A, Shidfar A, Chatterton RT, Blanco L, Meindl A, Helenowski I  et al.  Menstrual Phase and Menopausal Status Classification of Benign Breast Tissue Using Hormone-Regulated Gene Expression and Histomorphology: A Validation Study.  Ann Surg Oncol  2023 Aug;30(8):5215-5224. doi:10.1245/s10434-023-13192-1
17. Nemes S, Logan PE, Manchella MK, Mundada NS, La Joie R, Polsinelli AJ, Hammers DB, Koeppe RA, Foroud TM, Nudelman KN  et al.  Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.  Alzheimers Dement  2023 Jul 26;. doi:10.1002/alz.13403
18. Dage JL, Eloyan A, Thangarajah M, Hammers DB, Fagan AM, Gray JD, Schindler SE, Snoddy C, Nudelman KNH, Faber KM  et al.  Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.  Alzheimers Dement  2023 Jul 25;. doi:10.1002/alz.13399
19. Eloyan A, Thangarajah M, An N, Borowski BJ, Reddy AL, Aisen P, Dage JL, Foroud T, Ghetti B, Griffin P  et al.  White matter hyperintensities are higher among early-onset Alzheimer's disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Early-onset Alzheimer's Disease Study (LEADS).  Alzheimers Dement  2023 Jul 25;. doi:10.1002/alz.13402
20. Iverson GL, Kissinger-Knox A, Huebschmann NA, Castellani RJ, Gardner AJ  A narrative review of psychiatric features of traumatic encephalopathy syndrome as conceptualized in the 20th century.  Front Neurol  2023;14:1214814. pii:1214814
21. Sadleir KR, Vassar R  Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer's disease.  J Clin Invest  2023 Jul 17;133(14). pii:e171838
22. Parnell E, Culotta L, Forrest MP, Jalloul HA, Eckman BL, Loizzo DD, Horan KKE, Dos Santos M, Piguel NH, Tai DJC  et al.  Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.  Biol Psychiatry  2023 Jul 15;94(2):153-163. doi:10.1016/j.biopsych.2022.11.005
23. Castellani RJ, Perry G  The Teflon hypothesis.  Brain Commun  2023;5(4):fcad203. pii:fcad203
24. Zhang L, Flagan TM, Häkkinen S, Chu SA, Brown JA, Lee AJ, Pasquini L, Mandelli ML, Gorno-Tempini ML, Sturm VE  et al.  Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum.  Ann Neurol  2023 Jul 10;. doi:10.1002/ana.26738
25. Zhang H, Du Y, Qi L, Xiao S, Braun FK, Kogiso M, Huang Y, Huang F, Abdallah A, Suarez M  et al.  Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models.  J Transl Med  2023 Jul 06;21(1):444. pii:444
26. Chandra S, Di Meco A, Dodiya HB, Popovic J, Cuddy LK, Weigle IQ, Zhang X, Sadleir K, Sisodia SS, Vassar R  The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms.  Mol Neurodegener  2023 Jul 06;18(1):45. pii:45
27. Dahl R, Moore AC, Knight C, Mauger C, Zhang H, Schiltz GE, Koss WA, Bezprozvanny I  Positive Allosteric Modulator of SERCA Pump NDC-1173 Exerts Beneficial Effects in Mouse Model of Alzheimer's Disease.  Int J Mol Sci  2023 Jul 04;24(13). pii:11057
28. Høilund-Carlsen PF, Revheim ME, Costa T, Kepp KP, Castellani RJ, Perry G, Alavi A, Barrio JR  FDG-PET versus Amyloid-PET Imaging for Diagnosis and Response Evaluation in Alzheimer's Disease: Benefits and Pitfalls.  Diagnostics (Basel)  2023 Jul 03;13(13). pii:2254
29. Engelmeyer JR, Kerr A, Makowski-Woidan BA, Gill NP, Mesulam MM, Weintraub S, Zhang H, Lindquist L, Rogalski EJ  Medical characterization of cognitive SuperAgers: Investigating the medication profile of SuperAgers.  J Am Geriatr Soc  2023 Jul 03;. doi:10.1111/jgs.18496
30. Mesulam MM, Gefen T, Flanagan M, Castellani R, Jamshidi P, Barbieri E, Sridhar J, Kawles A, Weintraub S, Geula C  et al.  Frontotemporal Degeneration with Transactive Response DNA-Binding Protein Type C at the Anterior Temporal Lobe.  Ann Neurol  2023 Jul;94(1):1-12. doi:10.1002/ana.26677
31. Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR  et al.  Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia.  Alzheimers Dement  2023 Jul;19(7):2842-2852. doi:10.1002/alz.12898
32. Zouridakis A, Ayala I, Minogue G, Kawles A, Keszycki R, Macomber A, Bigio EH, Geula C, Mesulam MM, Gefen T  Shades of gray in human white matter.  J Comp Neurol  2023 Jun 27;. doi:10.1002/cne.25512
33. Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D  et al.  Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.  JCI Insight  2023 Jun 22;8(12). pii:e169937
34. Cahan JG, Vassar R, Bonakdarpour B  Lower Cerebrospinal Fluid Amyloid-β42 Predicts Sooner Time to Antipsychotic Use in Alzheimer's Disease.  J Alzheimers Dis Rep  2023;7(1):641-647. doi:10.3233/ADR-220064
35. Iverson GL, Jamshidi P, Fisher-Hubbard AO, Deep-Soboslay A, Hyde TM, Kleinman JE, deJong JL, Shepherd CE, Hazrati LN, Castellani RJ  Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.  Front Neurol  2023;14:1143882. pii:1143882
36. Keszycki R, Kawles A, Minogue G, Zouridakis A, Macomber A, Gill N, Vu M, Zhang H, Coventry C, Rogalski E  et al.  Distinct and shared neuropsychiatric phenotypes in FTLD-tauopathies.  Front Aging Neurosci  2023;15:1164581. pii:1164581
37. Polsinelli AJ, Wonderlin RJ, Hammers DB, Garcia AP, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Wang S  et al.  Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort.  Alzheimers Dement  2023 Jun 09;. doi:10.1002/alz.13344
38. Nelson MJ, Moeller S, Seckin M, Rogalski EJ, Mesulam MM, Hurley RS  The eyes speak when the mouth cannot: Using eye movements to interpret omissions in primary progressive aphasia.  Neuropsychologia  2023 Jun 06;184:108530. doi:10.1016/j.neuropsychologia.2023.108530
39. Conca F, Esposito V, Rundo F, Quaranta D, Muscio C, Manenti R, Caruso G, Lucca U, Galbussera AA, Di Tella S  et al.  Correction: Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I‑UDSNB 1.0): development and normative data.  Alzheimers Res Ther  2023 Jun 05;15(1):104. pii:104
40. Franzen S, Nuytemans K, Bourdage R, Caramelli P, Ellajosyula R, Finger E, Illán-Gala I, Loi SM, Morhardt D, Pijnenburg Y  et al.  Gaps in clinical research in frontotemporal dementia: A call for diversity and disparities-focused research.  Alzheimers Dement  2023 Jun 03;. doi:10.1002/alz.13129
41. Iverson GL, Castellani RJ, Cassidy JD, Schneider GM, Schneider KJ, Echemendia RJ, Bailes JE, Hayden KA, Koerte IK, Manley GT  et al.  Examining later-in-life health risks associated with sport-related concussion and repetitive head impacts: a systematic review of case-control and cohort studies.  Br J Sports Med  2023 Jun;57(12):810-821. doi:10.1136/bjsports-2023-106890
42. Hammers DB, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Kirby K, Aisen P, Dage JL, Foroud T  et al.  Profiling baseline performance on the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection.  Alzheimers Dement  2023 May 31;. doi:10.1002/alz.13160
43. Hammers DB, Nemes S, Diedrich T, Eloyan A, Kirby K, Aisen P, Kramer J, Nudelman K, Foroud T, Rumbaugh M  et al.  Learning slopes in early-onset Alzheimer's disease.  Alzheimers Dement  2023 May 27;. doi:10.1002/alz.13159
44. Nassan M, Piras IS, Rogalski E, Geula C, Mesulam MM, Huentelman M  Evaluating the Association Between Genetically Proxied Neurodevelopmental Language Phenotypes and the Risk of Primary Progressive Aphasia.  Neurology  2023 May 02;100(18):e1922-e1929. doi:10.1212/WNL.0000000000207136
45. Sonabend AM, Gould A, Amidei C, Ward R, Schmidt KA, Zhang DY, Gomez C, Bebawy JF, Liu BP, Bouchoux G  et al.  Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial.  Lancet Oncol  2023 May;24(5):509-522. doi:10.1016/S1470-2045(23)00112-2
46. Siddiqui OM, Baskaran AB, Lin KA, Najam N, Shah T, Beestrum ML, Thuluvath A, Bonakdarpour B, Kim M, Dietch Z  et al.  Cognitive Impairment in Liver Transplant Recipients With a History of Cirrhosis: A Systematic Review.  Transplant Direct  2023 May;9(5):e1479. pii:e1479
47. Karpouzian-Rogers T, Ho E, Novack M, Chinkers M, Bedjeti K, Nowinski C, Giordani B, Gershon R, Weintraub S  Baseline characterization of the ARMADA (Assessing Reliable Measurement in Alzheimer's Disease) study cohorts.  Alzheimers Dement  2023 May;19(5):1974-1982. doi:10.1002/alz.12816
48. Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME  et al.  Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.  Proc Natl Acad Sci U S A  2023 Apr 25;120(17):e2217396120. pii:e2217396120
49. Mesulam M, Thompson C, Weintraub S, Rogalski E  The Wernicke conundrum is misinterpreted.  Brain  2023 Apr 19;146(4):e21-e22. doi:10.1093/brain/awac482
50. Yuan Y, Jin A, Neal B, Feng X, Qiao Q, Wang H, Zhang R, Li J, Duan P, Cao L  et al.  Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial.  Nat Med  2023 Apr;29(4):973-981. doi:10.1038/s41591-023-02286-8