Northwestern University Feinberg School of Medicine
Mesulam Institute for Cognitive Neurology
& Alzheimer's Disease

Publications

  1. Iverson GL, Jamshidi P, Deep-Soboslay A, Hyde TM, Kleinman JE, Fisher-Hubbard AO, deJong JL, Shepherd CE, Hazrati LN, Castellani RJ  Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans.  Mil Med  2025 Nov 10;. pii:usaf553
  2. Chan KCG, Dodge HH, Sano M, Au R, Craft S, Levey AI, Weintraub S, Kukull WA, Saykin AJ, Barnes LL  Comparable performance of the NACC Uniform Data Set version 3 neuropsychological test battery in assessing longitudinal cognitive change for African American and White participants.  Alzheimers Dement  2025 Nov;21(11):e70889. pii:e70889
  3. Coty-Fattal Z, Smith H, McCord M, Mejia-Bautista M, Dittman D, Primdahl D, Conway K, Becker N, Ahrendsen JT, Santana-Santos L  et al.  Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept study.  J Neuropathol Exp Neurol  2025 Oct 24;. pii:nlaf122
  4. Ho EH, Karpouzian-Rogers T, Ayturk E, Bedjeti K, Weintraub S, Gershon R  NIH Toolbox Cognition Performance in Older Adults with Normal Cognition, Mild Cognitive Impairment, and Mild Dementia of the Alzheimer's Type: Results from the ARMADA Study.  Arch Clin Neuropsychol  2025 Oct 19;40(7):1279-1287. doi:10.1093/arclin/acaf035
  5. Thomas AB, Matthews AL, Brooks O, Winquist A, Nelson LA, Arias-Fontenot R, Buchwald D, Casaletto KB, Weintraub S, Heaton RK  et al.  Psychometric properties of the NIH Toolbox Cognition Battery composites in older adults at risk for Alzheimer's disease and related dementias: A systematic review.  Alzheimers Dement  2025 Oct;21(10):e70673. pii:e70673
  6. Fischer DL, Grinberg LT, Ahrendsen JT, Beach TG, Bieniek KF, Castellani RJ, Chkheidze R, Cobos I, Cohen M, Crary JF  et al.  Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers.  Alzheimers Dement  2025 Oct;21(10):e70734. pii:e70734
  7. Barbieri E, Kawles AS, Los M, Behn J, Geula C, Gefen T, Weintraub S, Mesulam MM  Atrophy progression in frontotemporal lobar degeneration-TDP-C with primary progressive aphasia.  Brain  2025 Oct 01;. pii:awaf369
  8. Corroon J, Bradley R, Grant I, Bancks MP, Jakob J, Auer R, Reis JP, Allen N, Yeh KH, Allison MA  Lifetime Cannabis Use and Incident Hypertension: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.  Hypertension  2025 Oct;82(10):1641-1652. doi:10.1161/HYPERTENSIONAHA.125.25005
  9. Bucaloiu A, Jamshidi P, Dixit K, Sukhanova M, Tariq H  Diagnostic utility of plasma circulating tumor DNA (ctDNA) in primary large B-cell lymphoma of the central nervous system (PCNS-LBCL): A paradigm shift?  Leuk Lymphoma  2025 Oct;66(10):1956-1959. doi:10.1080/10428194.2025.2508298
  10. Salvo JJ, Lakshman M, Holubecki AM, Saygin ZM, Mesulam MM, Braga RM  The ventral visual stream for reading converges on the transmodal language network.  bioRxiv  2025 Sep 23;. pii:2025.09.17.676937
  11. Khan F, Petrosyan E, Liu Y, Bahrami A, Taefi E, Geula C, Lesniak MS, Chen P  Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis.  Cancer Res  2025 Sep 18;. doi:10.1158/0008-5472.CAN-25-1791
  12. Flagan TM, Chu SA, Häkkinen S, Zhang L, McFall D, Rohrer JD, Brown JA, Lee AJ, Fernhoff K, Pasquini L  et al.  Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers.  Ann Clin Transl Neurol  2025 Sep 16;. doi:10.1002/acn3.70170
  13. Jeon S, Alia AO, Popovic J, Vassar R, Cuddy LK  ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice.  PLoS One  2025;20(9):e0330193. pii:e0330193
  14. Castellani RJ, Najem H, Heimberger AB, Jamshidi P  Myeloid-mediated cerebral amyloid vasculitis and the potential role of the immune response in brain atrophy.  J Clin Invest  2025 Sep 02;135(17). pii:e195137
  15. Cohen ML, Boulton AJ, Tyner CE, Slotkin J, Weintraub S, Gershon RC, Dodge HH, Tulsky DS  Cross-domain latent profiles of MCI and dementia are most differentiated by social and emotional functioning.  J Int Neuropsychol Soc  2025 Sep 01;:1-11. doi:10.1017/S1355617725101276
  16. Weintraub S, Gefen T, Geula C, Mesulam MM  The first 25 years of the Northwestern University SuperAging Program.  Alzheimers Dement  2025 Aug;21(8):e70312. pii:e70312
  17. Iverson GL, Jamshidi P, Deep-Soboslay A, Hyde TM, Kleinman JE, Hazrati LN, Castellani RJ  Postmortem tau in the CA2 region of the hippocampus in older adult men who participated in youth amateur American-style football.  J Alzheimers Dis  2025 Aug;106(3):1108-1119. doi:10.1177/13872877251351524
  18. Lagarde J, Maiti P, Schonhaut DR, Blazhenets G, Zhang J, Eloyan A, Thangarajah M, Taurone A, Allen IE, Soleimani-Meigooni DN  et al.  Amyloid PET in Sporadic Early- Versus Late-Onset Alzheimer's Disease: Comparison of the LEADS and ADNI Cohorts.  Ann Neurol  2025 Aug;98(2):236-248. doi:10.1002/ana.27233
  19. Bucko P, Novack MA, Ho EH, Ece B, Burleigh E, Mather MA, Karpouzian-Rogers T, Dworak EM, Pila S, Hosseinian Z  et al.  Identification and synthesis of end-of-life decision-making measures: a scoping review.  Front Med (Lausanne)  2025;12:1540486. pii:1540486
  20. Li E, Chakraborty A, Kohtz SJ, Cajigas I, Hinojosa-Gonzalez L, Shiau F, Bertossi R, Vassar RJ, Kessler JA, Ay F  et al.  Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains.  Nat Commun  2025 Jul 26;16(1):6902. pii:6902
  21. Kawles A, Zouridakis A, Nelson C, Keszycki R, Minogue G, Macomber A, Jamshidi P, Castellani RJ, Geula C, Gefen T  et al.  Dendritic location of dystrophic neurites in FTLD-TDP type C with annexinopathy.  Brain Pathol  2025 Jul 23;:e70032. doi:10.1111/bpa.70032
  22. Smith HL, Duckett DJ, Mejia-Bautista M, Alshawa A, Jamshidi P, Castellani RJ, Lukas RV, Chandler JP, Jennings LJ, Santana-Santos L  et al.  IDH-wildtype astrocytoma with FH mutation, epigenetic similarity to IDH-mutant astrocytoma, and hypermethylation of CDKN2A arising in the brainstem.  J Neuropathol Exp Neurol  2025 Jul 22;. pii:nlaf086
  23. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL  et al.  Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.  Genome Biol  2025 Jul 17;26(1):210. pii:210
  24. Fares J, Jamshidi P, Congivaram HT, Oyon D, Bautista MM, Kern RC, Brat DJ, Youngblood MW, Chandler JP  Primary papillary epithelial tumor of the sella harboring an EZH2 Y646F mutation.  Acta Neuropathol  2025 Jul 15;150(1):4. pii:4
  25. Castellani RJ, Kostelecky N, Ahrendsen JT, Nassan M, Jamshidi P, Iverson GL  Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review.  Brain Sci  2025 Jul 08;15(7). pii:729
  26. Hanson BA, Dang X, Jamshidi P, Steffens A, Copenhaver K, Orban ZS, Bustos B, Lubbe SJ, Castellani RJ, Koralnik IJ  Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson's disease.  JCI Insight  2025 Jul 08;10(13). pii:e189988
  27. Multz RA, Jamshidi P, Ahrendsen JT  Multiple sclerosis: a practical review for pathologists.  J Pathol Transl Med  2025 Jul;59(4):203-213. doi:10.4132/jptm.2025.05.20
  28. Chandra S, Popovic J, Singhal NK, Watkins EA, Dodiya HB, Weigle IQ, Salvo MA, Ramakrishnan A, Chen Z, Watson T  et al.  The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17.  J Clin Invest  2025 Jul 01;135(13). pii:e180826
  29. Vormittag-Nocito E, Duckett D, Castellani RJ, Ahrendsen JT, Lu X, Jennings LJ, Lukas RV, Magill ST, Santana-Santos L, Brat DJ  et al.  Meningiomas With Chromosomal Polysomies Reveal Nonrandom Gain of Chromosomes, Distinct Methylation Signature, and Lower Risk of Recurrence.  Mod Pathol  2025 Jul;38(7):100775. doi:10.1016/j.modpat.2025.100775
  30. Peng W, Bonakdarpour B  The Case of a 67-Year-Old Man With Memory Difficulties and Altered Sleep.  Ann Clin Transl Neurol  2025 Jul;12(7):1511-1513. doi:10.1002/acn3.70027
  31. Fernandopulle MS, Cotty-Fattal Z, Smith H, Mejia Bautista M, Ahrendsen JT, Jennings LJ, Santana-Santos L, Sukhanova M, Conway K, Primdahl D  et al.  Dual TERT promoter mutations in an oligodendroglioma, IDH-mutant, 1p/19q co-deleted.  J Neuropathol Exp Neurol  2025 Jul 01;84(7):658-660. doi:10.1093/jnen/nlae138
  32. Herrold AA, Aaronson AL, Bhaumik D, Durazzo T, Livengood SL, Ramic A, Riordan P, Jordan N, Parrish T, Mallinson T  et al.  A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial.  JMIR Res Protoc  2025 Jun 23;14:e64909. pii:e64909
  33. Mather MA, Ece B, Karpouzian-Rogers T, Ho EH, Bucko P, Dworak EM, Novack MA, Pila S, Hosseinian Z, Hanmer J  et al.  Measures of healthcare decision-making ability in cognitive aging: a scoping review from the Advancing Reliable Measurement in Cognitive Aging and Decision-Making Ability (ARMCADA) research initiative.  Front Public Health  2025;13:1582764. pii:1582764
  34. O'Conor R, Pack A, Russell AM, Oladejo D, Rogalski E, Morhardt D, Fortinsky RH, Lindquist LA, Persell SD, Wolf MS  Triadic Primary Care Encounters Managing Medications Among Individuals With Mild Cognitive Impairment and Dementia: Patient, Caregiver, and Clinician Perspectives.  Gerontologist  2025 Jun 12;65(7). pii:gnaf122
  35. Xu T, Su T, Soye BJD, Kandi S, Huang CF, Wilkins JT, Castellani RJ, Kafader JO, Patrie SM, Vassar R  et al.  The Proteoform Landscape of Tau from the Human Brain.  J Proteome Res  2025 Jun 06;24(6):2916-2925. doi:10.1021/acs.jproteome.5c00139
  36. Karunakaran DKP, Ley M, Guo J, Khatri A, Sadleir K, Popovic J, Upadhyay AK, Savas J, Procissi D, Atwal J  et al.  The UNC5C T835M mutation associated with Alzheimer's disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice.  Mol Neurodegener  2025 Jun 04;20(1):65. pii:65
  37. Wirtshafter HS, Solla SA, Disterhoft JF  A universal hippocampal memory code across animals and environments.  bioRxiv  2025 Jun 03;. pii:2024.10.24.620127
  38. Bonakdarpour B, Schafer R, Takarabe C, Barbieri E, Miller J, Miller SS  Virtual group singing programs for well-being in healthy older adults and persons with neurocognitive disorders during early COVID-19 pandemic: A perspective from Chicago.  J Alzheimers Dis  2025 Jun;105(3):904-922. doi:10.1177/13872877251333155
  39. Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L  et al.  X-chromosome-wide association study for Alzheimer's disease.  Mol Psychiatry  2025 Jun;30(6):2335-2346. doi:10.1038/s41380-024-02838-5
  40. Koh Y, Vázquez-Rosa E, Gao F, Li H, Chakraborty S, Tripathi SJ, Barker S, Bud Z, Bangalore A, Kandjoze UP  et al.  Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.  Proc Natl Acad Sci U S A  2025 May 27;122(21):e2417224122. pii:e2417224122
  41. Sadleir KR, Gomez KP, Edwards AE, Patel AJ, Ley ML, Khatri AW, Guo J, Mahesh S, Watkins EA, Popovic J  et al.  Annexin A6 membrane repair protein protects against amyloid-induced dystrophic neurites and tau phosphorylation in Alzheimer's disease model mice.  Acta Neuropathol  2025 May 24;149(1):51. pii:51
  42. Burt AL, Daly MP, Sherman JC, Schmahmann JD,   The Cerebellar Neuropsychiatric Rating Scale in the Spinocerebellar Ataxias.  Cerebellum  2025 May 05;24(4):94. doi:10.1007/s12311-025-01840-z
  43. Alshikho MJ, Haghighi N, Ravi R, Solomon VA, Rangel E, Pyne JD, Bista KC, Chang JF, Lippert RV, Cotton-Samuel D  et al.  Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study.  Pregnancy (Hoboken)  2025 May;1(3). pii:e70020
  44. van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM  et al.  Author Correction: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.  Nat Med  2025 May;31(5):1712. doi:10.1038/s41591-025-03664-0
  45. van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM  et al.  Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.  Nat Med  2025 May;31(5):1604-1616. doi:10.1038/s41591-025-03574-1
  46. Kragel JE, Lurie SM, Issa NP, Haider HA, Wu S, Tao JX, Warnke PC, Schuele S, Rosenow JM, Zelano C  et al.  Closed-loop control of theta oscillations enhances human hippocampal network connectivity.  Nat Commun  2025 Apr 30;16(1):4061. pii:4061
  47. Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P  et al.  Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.  Nat Commun  2025 Apr 25;16(1):3914. pii:3914
  48. Kim M, Rogers L, Batio S, Benavente JY, Bonham M, Zheng P, Lovett RM, Bailey SC, Kwasny MJ, Ladner DP  et al.  Trajectories of sleep disturbance and self-management of chronic conditions during COVID-19 among middle-aged and older adults.  Sci Rep  2025 Apr 10;15(1):12324. pii:12324
  49. Liu X, de Boer SCM, Cortez K, Poos JM, Illán-Gala I, Heuer H, Forsberg LK, Casaletto K, Memel M, Appleby BS  et al.  Sex differences in clinical phenotypes of behavioral variant frontotemporal dementia.  Alzheimers Dement  2025 Apr;21(4):e14608. pii:e14608
  50. Gettel C, Galske J, Araujo K, Dresden S, Dussetschleger J, Iannone L, Lai J, Martin P, Mignosa B, Muschong K  et al.  Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway.  Alzheimers Dement  2025 Apr;21(4):e70189. pii:e70189

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