Mesulam Institute Home > For Scientists & Trainees > Publications
Publications
Paranhos T, Katsumi Y, Brickhouse MJ, Eloyan A, Eckbo R, Zaitsev A, Du A, La Joie R, Thangarajah M, Taurone A et al.
EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease: An MRI-Based Prognostic Biomarker.
Neurology
2026 Oct 13;107(7):e218519. pii:e218519 Castellani RJ
Traumatic brain injury and Alzheimer's disease: The null hypothesis wins.
J Alzheimers Dis
2026 Sep 17;:13872877261489299. doi:10.1177/13872877261489299 Yaghoobi S, Salboukh F, Llyod-Jones D, Allen N, Jacobs DR, Launer LJ, Yaffe K, Mesulam MM, Gorelick PB, Bryan RN et al.
Early Life Vascular Risk and Midlife Markers of Brain Aging.
Stroke
2026 Sep 15;. doi:10.1161/STROKEAHA.126.055765 Ece B, Giordani B, Goldstein F, Weintraub S, Manly J, Dalton P, Parma V, Gershon RC, Ho EH
Evaluation of the NIH Toolbox Odor Identification Test in African American older adults with and without amnestic mild cognitive impairment.
J Alzheimers Dis
2026 Sep 11;:13872877261483176. doi:10.1177/13872877261483176 McQuail JA, Barnes CA, Bizon JL, Burke SN, Disterhoft JF, Foster TC, Huentelman M, Kaczorowski CC, Long JM, Moore SJ et al.
Individual Differences in Cognitive Aging Rodent Datasets (ID-CARD): A collaborative platform for behavioral analysis across the lifespan.
Neurobiol Aging
2026 Sep 10;169:27-36. doi:10.1016/j.neurobiolaging.2026.09.003 Rogalski E, Fegter O, Rademaker A, Bona M, Roberts AC
Lessons From the Communication Bridge Trials: Advancing Meaningful Dyadic Interventions Toward Implementation.
J Speech Lang Hear Res
2026 Sep 08;:1-10. doi:10.1044/2026_JSLHR-26-00074 Petersen J, Gupta SV, Apple AC, Cobia D, Dokucu ME, Donnelly ED, Gradishar WJ, Mihailovic M, Reilly JL, Voss JL et al.
Functional dysconnectivity in breast cancer patients undergoing hormone therapy.
J Clin Exp Neuropsychol
2026 Sep;48(7):673-695. doi:10.1080/13803395.2026.2617353 Mejia-Bautista M, Soto GS, Mitchell BI, Moravek MR, Conway K, Reyes I, Ahrendsen JT, Castellani RJ, Qi C, Jamshidi P
Disseminated BCGosis presenting as multiple intracranial lesions in an immunocompromised patient.
J Neuropathol Exp Neurol
2026 Sep 01;85(9):1045-1047. doi:10.1093/jnen/nlaf155 Iverson GL, Jamshidi P, Deep-Soboslay A, Hyde TM, Kleinman JE, Shepherd CE, Hazrati LN, Castellani RJ
Cortical subpial aging-related tau astrogliopathy in older adult men who participated in youth amateur American-style football.
J Neuropathol Exp Neurol
2026 Aug 01;85(8):868-880. doi:10.1093/jnen/nlag032 Zhao J, Zhang M, Vidano C, Takarabe C, Bonakdarpour B
Musical Museum: an integrative approach to emotional, intellectual and social stimulation for individuals with Alzheimer's disease and related disorders and their caregivers.
Front Neurol
2026;17:1849901. pii:1849901 Touroutoglou A, Katsumi Y, Hensel J, Schindler SE, Ibanez L, Brickhouse M, Eloyan A, Eckbo R, Zaitsev A, La Joie R et al.
Relationships of CSF biomarkers to cortical atrophy in early-onset Alzheimer's disease.
Alzheimers Dement
2026 Jul;22(7):e71479. pii:e71479 Umeres-Francia GE, Mejia-Bautista M, Jamshidi P, Ahrendsen JT
Ganglioglioma and gangliocytoma: a review for pathologists.
J Pathol Transl Med
2026 Jul;60(4):379-387. doi:10.4132/jptm.2026.06.06 Stocks J, Barbieri E, Los MA, Thompson CK, Gefen T, Geula C, Mesulam MM, Weintraub S
Neuropathology-specific language features in primary progressive aphasia.
Alzheimers Dement
2026 Jul;22(7):e71633. pii:e71633 Høilund-Carlsen PF, Alavi A, Andalib S, Castellani RJ, Costa T, de Girolamo G, Espay AJ, Neve RL, Perry G, Revheim ME et al.
Serious side effects of Alzheimer's immunotherapy demand scrutiny.
Ageing Res Rev
2026 Jul;119:103151. doi:10.1016/j.arr.2026.103151 Jategaonkar MS, Miller NH, Zur SE, Geula C, Penzes P, Zaccard CR
Nanotubular networks in the aging brain: from neuroprotection to neurodegeneration.
Front Hum Neurosci
2026;20:1864090. pii:1864090 Kim KS, Zhang J, Arrieta VA, Dmello C, Grabis E, Yabo YA, Wang S, Habashy K, Duffy J, Zhao J et al.
Glioma-intrinsic MAPK/ERK signaling promotes immunotherapy efficacy through T cell infiltration and interferon responses.
Nat Commun
2026 Jun 25;17(1). pii:7968 Rogalski E, Fegter O, Roberts AC, Bona M, Cummings E, Esparza M, Polley E, Rademaker A
Person-centered intervention response in primary progressive aphasia: A secondary analysis of the Communication Bridge-2 randomized clinical trial.
Alzheimers Dement (N Y)
2026;12(2):e70283. pii:e70283 Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R
Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.
Alzheimers Res Ther
2026 Jun 03;18(1). pii:184 Mejia-Bautista M, Loxas M, Jamshidi P, Duckett D, Wolinsky JP, Ahrendsen JT
A 40-year-old woman with a spinal mass.
Brain Pathol
2026 Jun 01;:e70111. doi:10.1111/bpa.70111 Minogue G, Zouridakis A, Nelson C, Kawles A, Keszycki R, Macomber A, Weintraub S, Gill N, Mao Q, Jamshidi P et al.
Syndrome-specific vulnerability of neuronal and glial 4-repeat frontotemporal lobar degeneration-tau.
Brain
2026 Jun 01;. pii:awag190 Friedman J, Jamshidi P, Huang W
Cushing disease and unilateral primary aldosteronism confounded by a nonfunctioning contralateral adrenal incidentaloma.
JCEM Case Rep
2026 Jun;4(6):luag114. pii:luag114 Lin M, Chiotis K, Maiti P, Zhang J, Blazhenets G, Rocha S, Shankar R, Amuiri A, Hammers DB, Eloyan A et al.
Tau topography subtypes account for clinical heterogeneity and longitudinal trajectories in early-onset Alzheimer's disease.
Brain Commun
2026;8(3):fcag176. pii:fcag176 Hammers DB, Polsinelli A, Eloyan A, Taurone A, Thangarajah M, Foroud T, Gao S, Beckett L, La Joie R, Touroutoglou A et al.
Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS.
Alzheimers Dement (Amst)
2026;18(2):e70342. pii:e70342 Hammers DB, Foster E, Eloyan A, Thangarajah M, Taurone A, Touroutoglou A, La Joie R, Beckett L, Gao S, Vemuri P et al.
Cognitive dispersion profiles and prediction of cognitive change in early-onset dementias: Results from LEADS.
Alzheimers Dement
2026 May;22(5):e71492. pii:e71492 Quiring ML, Edwards L, Bangen KJ, Ho EH, Carlsson CM, Galasko D, Weintraub S, Gershon R, Salmon DP
Effects of age and APOE ϵ4 genotype on the relationship between pulse pressure and executive function in older adults without dementia.
J Int Neuropsychol Soc
2026 May;32(4):301-310. doi:10.1017/S1355617726102008 Wang H, Walenski M, Litcofsky K, Mack JE, Mesulam MM, Thompson CK
Online comprehension of verbal time reference in primary progressive aphasia: Evidence from eyetracking.
J Neurolinguistics
2026 May;78. pii:101318 Dutt S, Leichter D, Cobigo Y, Wolf A, Kornak J, Clark A, Russell LL, Bouzigues A, Cash DM, Bocchetta M et al.
Individualized Atrophy-Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed-Effects Modeling.
Ann Neurol
2026 May;99(5):1315-1326. doi:10.1002/ana.78167 Split M, Kunicki ZJ, Ross D, Keszycki R, Prieto S, Manoochehri M, De Vito AN, Appleby B, Hales CM, Onyike C et al.
Factors influencing accelerated progression in behavioral variant frontotemporal dementia.
J Neurol
2026 Apr 30;273(5). pii:297 Wirtshafter HS, Mehta MR, Solla SA, Disterhoft JF
Hippocampal conditioning code dominates and disrupts the place code.
bioRxiv
2026 Apr 20;. pii:2026.02.17.706430 Barbieri E, Kawles AS, Los M, Behn J, Geula C, Gefen T, Weintraub S, Mesulam MM
Atrophy progression in frontotemporal lobar degeneration-TDP-C with primary progressive aphasia.
Brain
2026 Apr 07;149(4):1194-1207. doi:10.1093/brain/awaf369 Chan CK, Glover CM, Parker M, Grill JD, Langbaum JB, Morhardt DJ, Okonkwo O, Farrar-Edwards D, Wang S
Outreach, Recruitment and Engagement Cores of NIA-designated Alzheimer's Disease Research Centers: Current strategies and future directions.
Alzheimers Dement
2026 Apr;22(4):e71238. pii:e71238 De Coster W, Van den Broeck M, Baker M, Ghayal NB, Wynants S, Batzler A, Pottier C, Alidadiani S, Küçükali F, Jenkins GD et al.
A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions.
Nat Genet
2026 Apr;58(4):726-736. doi:10.1038/s41588-026-02537-7 Disouky A, Sanborn MA, Sabitha KR, Mostafa MM, Ayala IA, Bennett DA, Lu Y, Zhou Y, Keene CD, Weintraub S et al.
Human hippocampal neurogenesis in adulthood, ageing and Alzheimer's disease.
Nature
2026 Apr;652(8112):1264-1273. doi:10.1038/s41586-026-10169-4 Alvarez FR, Nayman EI, Chen YH, Chen QC, Jamshidi P, Dixit K, Tariq H
Polymorphic central nervous system (CNS) immune deficiency/dysregulation-associated lymphoproliferative disorders show a uniquely aggressive clinicopathologic profile compared to their extra-CNS counterparts.
Hum Pathol
2026 Apr;170:106051. doi:10.1016/j.humpath.2026.106051 Smith HL, Duckett DJ, Mejia-Bautista M, Alshawa A, Jamshidi P, Castellani RJ, Lukas RV, Chandler JP, Jennings LJ, Santana-Santos L et al.
IDH-wildtype astrocytoma with FH mutation, epigenetic similarity to IDH-mutant astrocytoma, and hypermethylation of CDKN2A arising in the brainstem.
J Neuropathol Exp Neurol
2026 Apr 01;85(4):398-401. doi:10.1093/jnen/nlaf086 Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R
Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.
bioRxiv
2026 Mar 18;. pii:2026.03.16.711596 Song R, Dapash M, Jamshidi P, Gondi V, Lukas RV, Khan OH
Survival and function in elderly patients with GBM: the role of surgical resection with contemporary multimodal therapy.
J Neurooncol
2026 Mar 17;177(2). pii:62 Gutstein DB, Iorga M, Stocks J, Gill N, Sleeman J, Gefen TD, Los M, Nelson C, Geula C, Weintraub S et al.
Identifying neuropathologic disease in primary progressive aphasia using narrative speech.
Alzheimers Dement
2026 Mar;22(3):e71294. pii:e71294 George E, Braun M, Vassar R, Fox CK, Siegel DH, Mathes E, Frieden IJ, Hess CP, ,
Multi-center study of long-term evolution of neuroimaging findings in PHACE syndrome.
Eur J Paediatr Neurol
2026 Mar;61:1-7. doi:10.1016/j.ejpn.2026.02.004 Salvo MA, Cuddy LK, Prokopenko D, Watkins E, Tanzi RE, Vassar R
Alzheimer's disease-linked ACE variants increase ACE1 catalytic activity and production of angiotensin II.
J Biol Chem
2026 Mar;302(3):111171. pii:111171 Kawles A, Nelson C, Ayala I, Barbieri E, Castellani R, Geula C, Gefen T, Mesulam MM
Anatomical Progression of Neuropathology in FTLD-TDP Type C and Linkage to Annexin A11.
Ann Neurol
2026 Mar;99(3):639-655. doi:10.1002/ana.78095 Coty-Fattal Z, Smith H, McCord M, Mejia-Bautista M, Dittman D, Primdahl D, Conway K, Becker N, Ahrendsen JT, Santana-Santos L et al.
Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept study.
J Neuropathol Exp Neurol
2026 Mar 01;85(3):280-284. doi:10.1093/jnen/nlaf122 Bertholim-Nasciben L, Wang L, Xu W, Ramirez A, Moura S, Lu L, Liu X, Rajabli F, Celis K, Gearing M et al.
Enhanced Hi-C Capture Analysis reveals complex regulatory architecture at the PICALM_EED locus for Alzheimer's disease.
bioRxiv
2026 Feb 17;. pii:2026.02.14.705927 Youngblood MW, Tripathi S, Najem H, Congivaram H, Gomez M, Sears TK, Hurley L, Billingham LK, Silvers C, Wang W et al.
STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways.
Nat Commun
2026 Feb 12;17(1). pii:2685 Rao NR, Santiago-Marrero I, DeGulis O, Nomura T, Goyal K, Lee S, Hark TJ, Dynes JC, Dexter EX, Dulewicz M et al.
Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer's disease models.
Sci Transl Med
2026 Feb 11;18(836):eadp3984. doi:10.1126/scitranslmed.adp3984 Macomber A, Zouridakis A, Lubbat V, Minogue G, Kawles A, Keszycki R, Nelson C, Gill N, Gutstein D, Castellani R et al.
Vulnerability of anterior cingulate Von Economo neurons to FTLD-tauopathies in behavioral variant frontotemporal dementia.
Cereb Cortex
2026 Feb 09;36(2). pii:bhag011 Dworak EM, Pila S, Novack MA, Hosseinian Z, Ho EH, Ece B, Karpouzian-Rogers T, Mather MA, Han YC, Bucko P et al.
A scoping review of emotion and non-cognitive measures of decision-making ability in older adults by the ARMCADA study.
Front Public Health
2026;14:1718861. pii:1718861 Hammers DB, Eloyan A, Thangarajah M, Taurone A, Gao S, Beckett L, Kirby K, Dage JL, Nudelman K, Aisen P et al.
Relationship between age and severity of cognitive impairment at diagnosis for early-onset and late-onset Alzheimer's disease: Comparison of LEADS and ADNI.
Alzheimers Dement
2026 Feb;22(2):e71160. pii:e71160 Arrieta VA, Benotmane JK, Du R, Habashy KJ, Zhao J, Najem H, Wang S, Hou D, Katz JL, Vázquez-Cervantes GI et al.
Integrated immune profiling of chordomas reveals spatially organized niches and functional heterogeneity.
Neuro Oncol
2026 Feb 01;28(2):440-453. doi:10.1093/neuonc/noaf213 Castellani RJ, Bharadwaj RA, Fisher-Hubbard AO, Deep-Soboslay A, Hyde TM, Kleinman JE, Hazrati LN, Iverson GL
Hyperphosphorylated tau and amyloid-β proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository.
J Alzheimers Dis
2026 Feb;109(4):1858-1873. doi:10.1177/13872877251411332