Publications

  1. Coty-Fattal Z, Smith H, McCord M, Mejia-Bautista M, Dittman D, Primdahl D, Conway K, Becker N, Ahrendsen JT, Santana-Santos L  et al.  Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept study.  J Neuropathol Exp Neurol  2026 Mar 01;85(3):280-284. doi:10.1093/jnen/nlaf122
  2. Youngblood MW, Tripathi S, Najem H, Congivaram H, Gomez M, Sears TK, Hurley L, Billingham LK, Silvers C, Wang W  et al.  STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways.  Nat Commun  2026 Feb 12;. doi:10.1038/s41467-026-69296-1
  3. Rao NR, Santiago-Marrero I, DeGulis O, Nomura T, Goyal K, Lee S, Hark TJ, Dynes JC, Dexter EX, Dulewicz M  et al.  Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer's disease models.  Sci Transl Med  2026 Feb 11;18(836):eadp3984. doi:10.1126/scitranslmed.adp3984
  4. Macomber A, Zouridakis A, Lubbat V, Minogue G, Kawles A, Keszycki R, Nelson C, Gill N, Gutstein D, Castellani R  et al.  Vulnerability of anterior cingulate Von Economo neurons to FTLD-tauopathies in behavioral variant frontotemporal dementia.  Cereb Cortex  2026 Feb 09;36(2). pii:bhag011
  5. George E, Braun M, Vassar R, Fox CK, Siegel DH, Mathes E, ,   Multi-center study of long-term evolution of neuroimaging findings in PHACE syndrome.  Eur J Paediatr Neurol  2026 Feb 07;61:1-7. doi:10.1016/j.ejpn.2026.02.004
  6. Dworak EM, Pila S, Novack MA, Hosseinian Z, Ho EH, Ece B, Karpouzian-Rogers T, Mather MA, Han YC, Bucko P  et al.  A scoping review of emotion and non-cognitive measures of decision-making ability in older adults by the ARMCADA study.  Front Public Health  2026;14:1718861. pii:1718861
  7. Hammers DB, Eloyan A, Thangarajah M, Taurone A, Gao S, Beckett L, Kirby K, Dage JL, Nudelman K, Aisen P  et al.  Relationship between age and severity of cognitive impairment at diagnosis for early-onset and late-onset Alzheimer's disease: Comparison of LEADS and ADNI.  Alzheimers Dement  2026 Feb;22(2):e71160. pii:e71160
  8. Castellani RJ, Bharadwaj RA, Fisher-Hubbard AO, Deep-Soboslay A, Hyde TM, Kleinman JE, Hazrati LN, Iverson GL  Hyperphosphorylated tau and amyloid-β proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository.  J Alzheimers Dis  2026 Feb;109(4):1858-1873. doi:10.1177/13872877251411332
  9. Dutt S, Leichter D, Cobigo Y, Wolf A, Kornak J, Clark A, Russell LL, Bouzigues A, Cash DM, Bocchetta M  et al.  Individualized Atrophy-Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed-Effects Modeling.  Ann Neurol  2026 Jan 29;. doi:10.1002/ana.78167
  10. Chiotis K, Blazhenets G, Soleimani-Meigooni DN, Aisen PS, Amuiri A, Atri A, Beckett L, Brickhouse M, Clark DG, Dage JL  et al.  Distinct Tau PET Dynamics in Early vs. Late Age-of-Onset Alzheimer's disease.  medRxiv  2026 Jan 26;. pii:2026.01.25.26344738
  11. Alvarez FR, Nayman EI, Chen YH, Chen QC, Jamshidi P, Dixit K, Tariq H  Polymorphic central nervous system (CNS) immune deficiency/dysregulation-associated lymphoproliferative disorders show a uniquely aggressive clinicopathologic profile compared to their extra-CNS counterparts.  Hum Pathol  2026 Jan 22;170:106051. doi:10.1016/j.humpath.2026.106051
  12. Petersen J, Gupta SV, Apple AC, Cobia D, Dokucu ME, Donnelly ED, Gradishar WJ, Mihailovic M, Reilly JL, Voss JL  et al.  Functional dysconnectivity in breast cancer patients undergoing hormone therapy.  J Clin Exp Neuropsychol  2026 Jan 21;:1-23. doi:10.1080/13803395.2026.2617353
  13. Salvo MA, Cuddy LK, Prokopenko D, Watkins E, Tanzi RE, Vassar R  Alzheimer's disease-linked ACE variants increase ACE1 catalytic activity and production of angiotensin II.  J Biol Chem  2026 Jan 20;302(3):111171. pii:111171
  14. Salvi C, Luchini SA, Pestilli F, Hanekamp S, Parrish T, Beeman M, Grafman J  The white matter of Aha! moments.  BMC Psychol  2026 Jan 20;14(1):151. pii:151
  15. Chaubey K, Vázquez-Rosa E, Tripathi SJ, Shin MK, Yu Y, Dhar M, Chakraborty S, Yamakawa M, Wang X, Sridharan PS  et al.  Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain.  Cell Rep Med  2026 Jan 20;7(1):102535. pii:102535
  16. Khan F, Petrosyan E, Liu Y, Bahrami A, Taefi E, Geula C, Lesniak MS, Chen P  Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis.  Cancer Res  2026 Jan 02;86(1):12-21. doi:10.1158/0008-5472.CAN-25-1791
  17. Kawles A, Zouridakis A, Nelson C, Keszycki R, Minogue G, Macomber A, Jamshidi P, Castellani RJ, Geula C, Gefen T  et al.  Dendritic location of dystrophic neurites in FTLD-TDP type C with annexinopathy.  Brain Pathol  2026 Jan;36(1):e70032. pii:e70032
  18. Mejia-Bautista M, Soto GS, Mitchell BI, Moravek MR, Conway K, Reyes I, Ahrendsen JT, Castellani RJ, Qi C, Jamshidi P  Disseminated BCGosis presenting as multiple intracranial lesions in an immunocompromised patient.  J Neuropathol Exp Neurol  2025 Dec 31;. pii:nlaf155
  19. Duckett D, Santana-Santos L, McCord M, Smith V, Lopes MBS, Youngblood MW, Magill ST, Chandler JP, Heimberger AB, Lukas R  et al.  Development, validation, and utility of a clinically applicable methylation classifier for recurrence risk prediction in meningiomas.  Acta Neuropathol Commun  2025 Dec 29;13(1):259. pii:259
  20. Grant RA, Runyan CE, Minogue GA, Stoolman JS, Watanabe S, Chen F, Senkow KJ, Cusick L, Schleck MJ, Nafikova R  et al.  Influenza A infection accelerates disease-associated microglia formation during physiological aging.  bioRxiv  2025 Dec 14;. pii:2025.12.11.693336
  21. Ulugut H, Younes K, Montembeault M, Bertoux M, Irish M, Kumfor F, Fumagalli GG, Samanci B, Illán-Gala I, Thompson JC  et al.  Clinical recognition of frontotemporal dementia with right temporal predominance: a consensus statement from the International Working Group.  Commun Med (Lond)  2025 Dec 12;5(1):523. pii:523
  22. Selvadurai LP, Burt AL, Daly MP, Sherman JC, Schmahmann JD  The Cerebellar Neuropsychiatric Rating Scale Version 2: Development and Validation.  Cerebellum  2025 Dec 05;24(6):185. doi:10.1007/s12311-025-01930-y
  23. Njamnshi WY, Chiotis K, Tsoy E, Blazhenets G, Maiti P, Zhang J, Allen IE, Rocha S, Shankar RP, Amuiri A  et al.  Tablet-based Cognitive Assessment Tool (TabCAT) in a multisite study of early-onset Alzheimer's disease.  Alzheimers Dement  2025 Dec;21(12):e71012. pii:e71012
  24. Flagan TM, Chu SA, Häkkinen S, Zhang L, McFall D, Rohrer JD, Brown JA, Lee AJ, Fernhoff K, Pasquini L  et al.  Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers.  Ann Clin Transl Neurol  2025 Dec;12(12):2575-2588. doi:10.1002/acn3.70170
  25. Kawles A, Nelson C, Ayala I, Barbieri E, Castellani R, Geula C, Gefen T, Mesulam MM  Anatomical Progression of Neuropathology in FTLD-TDP Type C and Linkage to Annexin A11.  Ann Neurol  2025 Nov 26;. doi:10.1002/ana.78095
  26. Iverson GL, Jamshidi P, Deep-Soboslay A, Hyde TM, Kleinman JE, Fisher-Hubbard AO, deJong JL, Shepherd CE, Hazrati LN, Castellani RJ  Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans.  Mil Med  2025 Nov 10;. pii:usaf553
  27. Chan KCG, Dodge HH, Sano M, Au R, Craft S, Levey AI, Weintraub S, Kukull WA, Saykin AJ, Barnes LL  Comparable performance of the NACC Uniform Data Set version 3 neuropsychological test battery in assessing longitudinal cognitive change for African American and White participants.  Alzheimers Dement  2025 Nov;21(11):e70889. pii:e70889
  28. Ho EH, Karpouzian-Rogers T, Ayturk E, Bedjeti K, Weintraub S, Gershon R  NIH Toolbox Cognition Performance in Older Adults with Normal Cognition, Mild Cognitive Impairment, and Mild Dementia of the Alzheimer's Type: Results from the ARMADA Study.  Arch Clin Neuropsychol  2025 Oct 19;40(7):1279-1287. doi:10.1093/arclin/acaf035
  29. Thomas AB, Matthews AL, Brooks O, Winquist A, Nelson LA, Arias-Fontenot R, Buchwald D, Casaletto KB, Weintraub S, Heaton RK  et al.  Psychometric properties of the NIH Toolbox Cognition Battery composites in older adults at risk for Alzheimer's disease and related dementias: A systematic review.  Alzheimers Dement  2025 Oct;21(10):e70673. pii:e70673
  30. Fischer DL, Grinberg LT, Ahrendsen JT, Beach TG, Bieniek KF, Castellani RJ, Chkheidze R, Cobos I, Cohen M, Crary JF  et al.  Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers.  Alzheimers Dement  2025 Oct;21(10):e70734. pii:e70734
  31. Barbieri E, Kawles AS, Los M, Behn J, Geula C, Gefen T, Weintraub S, Mesulam MM  Atrophy progression in frontotemporal lobar degeneration-TDP-C with primary progressive aphasia.  Brain  2025 Oct 01;. pii:awaf369
  32. Corroon J, Bradley R, Grant I, Bancks MP, Jakob J, Auer R, Reis JP, Allen N, Yeh KH, Allison MA  Lifetime Cannabis Use and Incident Hypertension: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.  Hypertension  2025 Oct;82(10):1641-1652. doi:10.1161/HYPERTENSIONAHA.125.25005
  33. Bucaloiu A, Jamshidi P, Dixit K, Sukhanova M, Tariq H  Diagnostic utility of plasma circulating tumor DNA (ctDNA) in primary large B-cell lymphoma of the central nervous system (PCNS-LBCL): A paradigm shift?  Leuk Lymphoma  2025 Oct;66(10):1956-1959. doi:10.1080/10428194.2025.2508298
  34. Salvo JJ, Lakshman M, Holubecki AM, Saygin ZM, Mesulam MM, Braga RM  The ventral visual stream for reading converges on the transmodal language network.  bioRxiv  2025 Sep 23;. pii:2025.09.17.676937
  35. Jeon S, Alia AO, Popovic J, Vassar R, Cuddy LK  ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice.  PLoS One  2025;20(9):e0330193. pii:e0330193
  36. Arrieta VA, Benotmane JK, Du R, Habashy KJ, Zhao J, Najem H, Wang S, Hou D, Katz JL, Vázquez-Cervantes GI  et al.  Integrated immune profiling of chordomas reveals spatially organized niches and functional heterogeneity.  Neuro Oncol  2025 Sep 11;. pii:noaf213
  37. Castellani RJ, Najem H, Heimberger AB, Jamshidi P  Myeloid-mediated cerebral amyloid vasculitis and the potential role of the immune response in brain atrophy.  J Clin Invest  2025 Sep 02;135(17). pii:e195137
  38. Weintraub S, Gefen T, Geula C, Mesulam MM  The first 25 years of the Northwestern University SuperAging Program.  Alzheimers Dement  2025 Aug;21(8):e70312. pii:e70312
  39. Iverson GL, Jamshidi P, Deep-Soboslay A, Hyde TM, Kleinman JE, Hazrati LN, Castellani RJ  Postmortem tau in the CA2 region of the hippocampus in older adult men who participated in youth amateur American-style football.  J Alzheimers Dis  2025 Aug;106(3):1108-1119. doi:10.1177/13872877251351524
  40. Lagarde J, Maiti P, Schonhaut DR, Blazhenets G, Zhang J, Eloyan A, Thangarajah M, Taurone A, Allen IE, Soleimani-Meigooni DN  et al.  Amyloid PET in Sporadic Early- Versus Late-Onset Alzheimer's Disease: Comparison of the LEADS and ADNI Cohorts.  Ann Neurol  2025 Aug;98(2):236-248. doi:10.1002/ana.27233
  41. Bucko P, Novack MA, Ho EH, Ece B, Burleigh E, Mather MA, Karpouzian-Rogers T, Dworak EM, Pila S, Hosseinian Z  et al.  Identification and synthesis of end-of-life decision-making measures: a scoping review.  Front Med (Lausanne)  2025;12:1540486. pii:1540486
  42. Li E, Chakraborty A, Kohtz SJ, Cajigas I, Hinojosa-Gonzalez L, Shiau F, Bertossi R, Vassar RJ, Kessler JA, Ay F  et al.  Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains.  Nat Commun  2025 Jul 26;16(1):6902. pii:6902
  43. Smith HL, Duckett DJ, Mejia-Bautista M, Alshawa A, Jamshidi P, Castellani RJ, Lukas RV, Chandler JP, Jennings LJ, Santana-Santos L  et al.  IDH-wildtype astrocytoma with FH mutation, epigenetic similarity to IDH-mutant astrocytoma, and hypermethylation of CDKN2A arising in the brainstem.  J Neuropathol Exp Neurol  2025 Jul 22;. pii:nlaf086
  44. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL  et al.  Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.  Genome Biol  2025 Jul 17;26(1):210. pii:210
  45. Fares J, Jamshidi P, Congivaram HT, Oyon D, Bautista MM, Kern RC, Brat DJ, Youngblood MW, Chandler JP  Primary papillary epithelial tumor of the sella harboring an EZH2 Y646F mutation.  Acta Neuropathol  2025 Jul 15;150(1):4. pii:4
  46. Castellani RJ, Kostelecky N, Ahrendsen JT, Nassan M, Jamshidi P, Iverson GL  Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review.  Brain Sci  2025 Jul 08;15(7). pii:729
  47. Hanson BA, Dang X, Jamshidi P, Steffens A, Copenhaver K, Orban ZS, Bustos B, Lubbe SJ, Castellani RJ, Koralnik IJ  Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson's disease.  JCI Insight  2025 Jul 08;10(13). pii:e189988
  48. Multz RA, Jamshidi P, Ahrendsen JT  Multiple sclerosis: a practical review for pathologists.  J Pathol Transl Med  2025 Jul;59(4):203-213. doi:10.4132/jptm.2025.05.20
  49. Chandra S, Popovic J, Singhal NK, Watkins EA, Dodiya HB, Weigle IQ, Salvo MA, Ramakrishnan A, Chen Z, Watson T  et al.  The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17.  J Clin Invest  2025 Jul 01;135(13). pii:e180826
  50. Vormittag-Nocito E, Duckett D, Castellani RJ, Ahrendsen JT, Lu X, Jennings LJ, Lukas RV, Magill ST, Santana-Santos L, Brat DJ  et al.  Meningiomas With Chromosomal Polysomies Reveal Nonrandom Gain of Chromosomes, Distinct Methylation Signature, and Lower Risk of Recurrence.  Mod Pathol  2025 Jul;38(7):100775. doi:10.1016/j.modpat.2025.100775

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