News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Mesulam Center for Cognitive Neurology and Alzheimer's Disease. The links below take you to articles where you can learn more about our members' latest achievements, awards and honors.
Northwestern Medicine scientists have discovered that an existing therapy used to treat Alzheimer’s disease might also work on patients with Primary Progressive Aphasia, a type of dementia that destroys language and currently has no treatment.
- 02.01.2019 Brain & Life
The Memory Ensemble, a collaboration between Darby Morhardt, PhD, of the Mesulam Center for Cognitive Neurology and Alzheimer's Disease, and Christine Dunford, PhD, a co-founder of the Lookingglass Theatre Company, was featured, highlighting the preliminary research published in Research in Drama Education: The Journal of Applied Theatre and Performance in June 2017.
The 8th Annual Les Turner Symposium brought together investigators, clinicians, patients and families to share the latest discoveries in ALS research, promote scientific collaboration and provide patient education.
- 10.02.2018 Northwestern Now
Northwestern University has received a $12.6 million grant from the National Institute on Aging at the National Institutes of Health (NIH) to study the role of protein quality control in human aging and neurodegenerative diseases such as Alzheimer’s disease.
- 09.12.2018 Chicago Tonight - WTTW
Despite decades of research and lack of a treatment to cure or slow the progression of the disease, researchers, caregivers and advocates are optimistic about the future. “I see a treatment, it’s going to happen. Scientists are very close,” said William Klein, a professor at Northwestern University. “I believe we’re on a positive path,” said Harry John, CEO of the Alzheimer’s Association. “We’ve got a lot to do but we’re on a positive path.”
- 08.17.2018 Reuters
The new findings highlight the need for more studies involving larger groups of patients, said Dr. Borna Bonakdarpour, an assistant professor of neurology at Northwestern University’s Cognitive Neurology and Alzheimer’s Disease Center. Bonakdarpour believes that music therapy can also be used to improve social interactions. “We are doing some interventions here to see if it can improve interactions between patients and caregivers,” he said. “We have preliminary data that suggests it helps.”
- Music can call back loved ones lost in Alzheimer’s darkness: ‘So much we can do to improve quality of life’06.11.2018 Chicago Tribune
Intrigued by the potantial benefits, Dr. Borna Bonakdarpour, a neurologist with Northwestern University’s Feinberg School of Medicine, put together a music therapy study this spring at Silverado Orchard Park Memory Care Community in Morton Grove. Each week for 12 weeks, the Evanston-based nonprofit Institute for Therapy Through the Arts held concerts for 10 Silverado residents. The musicians are specially trained to apply their skills to therapy, often by interacting with patients during performances, and getting them to beat on drums, sing, and dance. The $84,000 program is funded by an anonymous donor.
Feinberg met its goal of raising $10 million for the newly renamed Mesulam Cognitive Neurology and Alzheimer’s Disease Center, naming the Center after its director, M. Marsel Mesulam, MD.
- 04.16.2018 The Washington Post
It’s pretty extraordinary for people in their 80s and 90s to keep the same sharp memory as someone several decades younger, so scientists are peeking into the brains of“superagers” who do to uncover their secret. The work is the flip side of the disappointing hunt for new drugs to fight or prevent Alzheimer’s disease. Instead of tackling that problem, “why don’t we figure out what it is we might need to do to maximize our memory?” said neuroscientist Emily Rogalski, who leads the SuperAging study at Northwestern University in Chicago.
- 02.22.2018 Associated Press
WASHINGTON (AP) — It’s pretty extraordinary for people in their 80s and 90s to keep the same sharp memory as someone several decades younger, and now scientists are peeking into the brains of these “superagers” to uncover their secret. The work is the flip side of the disappointing hunt for new drugs to fight or prevent Alzheimer’s disease. Instead, “why don’t we figure out what it is we might need to do to maximize our memory?” said neuroscientist Emily Rogalski, who leads the SuperAging study at Northwestern University in Chicago.
- 02.04.2018 National Public Radio (Boston)
Dr. Darby Morhardt, professor at the Cognitive Neurology and Alzheimer's Disease Center at Northwestern University's Feinberg School of Medicine.
- 12.14.2017 Science Magazine
Phyllis Zee, a neurologist and neuroscientist at Northwestern University in Chicago, Illinois, says the research connects a lot of dots between sleep and memory. She’s curious whether the results will hold up in adults who are at risk for neurological conditions such as Alzheimer’s disease.
- 12.14.2017 The Washington Post
For nine years, these experts have been examining “SuperAgers” — men and women over age 80 whose memories are as good — or better — than people 20 to 30 years younger. Every couple of years, the group fills out surveys about their lives and gets a battery of neuropsychological tests, brain scans and a neurological examination, among other evaluations. “When we started this project, we weren’t really sure we could find these individuals,” said Emily Rogalski, an associate professor at the Cognitive Neurology and Alzheimer’s Disease Center at Northwestern’s Feinberg School of Medicine.
- 11.15.2017 Newsweek
"This is one of the first clear-cut genetic mutations in human beings that acts upon aging and aging-related disease," Dr. Douglas Vaughan told Newsweek. Vaughan is a cardiologist at Northwestern University Feinberg School of Medicine and one of the lead authors of the study, which was published in Science Advances on Wednesday. SERPINE1 makes a protein called plasminogen activator inhibitor-1, or PAI-1, which may play a role in diabetes and Alzheimer's, he noted.
- 11.06.2017 TODAY
Margaret and Mark Zumdahl have made countless memories during their 25-year marriage, but Margaret, who lives with Alzheimer’s, is slowly starting to lose those memories. Thanks to a special program at Northwestern's Cognitive Neurology and Alzheimer's Disease Center, the couple is receiving help to deal with the disease.
A study has identified a new mechanism for how a gene mutation leads to the death of neurons in amyotrophic lateral sclerosis and a related form of dementia.
A new study shows that a neurodegenerative syndrome in older adults, frontotemporal dementia, shares several fundamental features with another neurodegenerative disease usually seen in children.
According to a new study, normal agers lost volume in the cortex, which contains neurons, twice as fast as SuperAgers, a rare group of older people whose memories are as sharp as those decades younger.
- 03.31.2017 The New York Times
“If I had your stem cells and created a heart, liver, lung and an ovary, I could test 10 different drugs at 10 different doses on you and say, ‘Here’s the drug that will help your Alzheimer’s or Parkinson’s or diabetes,’ ” the lead investigator, Teresa K. Woodruff, said in a report about the research on the Northwestern University website. “It’s the ultimate personalized medicine, a model of your body for testing drugs.”
A new review, published in Nature Reviews Neurology, outlines how upper motor neuron degeneration is an important feature in ALS pathology, and could be key to developing better diagnostic tools and treatments for ALS.
“Truly, Northwestern University Feinberg School of Medicine is an institution on the rise,” said Eric G. Neilson, MD, vice president for Medical Affairs and Lewis Landsberg Dean. See some of the medical school's notable moments from 2016.
- 11.28.2016 Fox News (National)
Some older people who have signs of Alzheimer's disease in their brains may actually have pretty good memories, a small new study suggests. The results suggest that some individuals with Alzheimer's disease may be protected against some of its symptoms, like memory problems, said lead study author Changiz Geula, a professor of cognitive neurology at Northwestern University Feinberg School of Medicine in Chicago, Illinois.
- 11.22.2016 Huffington Post
“It appears that some elderly individuals are immune to the effects of Alzheimer’s pathology,” said neurologist Changiz Geula, of Northwestern University Feinberg School of Medicine, who presented the findings Tuesday at the annual meeting of the Society for Neuroscience in San Diego.
The National Institute on Aging has renewed funding for the Cognitive Neurology and Alzheimer’s Disease Center, supporting an additional five years of research, and marking 25 years of continuous grant support.
- 08.08.2016 The New York Times
Can you keep the love light shining after your partner’s brain has begun to dim? Just ask Denise Tompkins of Naperville, Ill., married 36 years to John, now 69, who has Alzheimer’s disease. The Tompkinses participated in an unusual eight-week storytelling workshop at Northwestern University that is helping to keep the spark of love alive in couples coping with the challenges of encroaching dementia. Every week participants are given a specific assignment to write a brief story about events in their lives that they then share with others in the group. The program culminates with a moving, often funny, 20-minute written story read alternately by the partners in each couple in front of an audience. The storytelling workshop, which started in January of 2014, was the brainchild of Lauren Dowden, then an intern in social work at Northwestern’s Cognitive, Neurological and Alzheimer’s Disease Center.
- 06.03.2016 WTTW Chicago Tonight
The race to find a cure or prevention for Alzheimer's disease is happening all around the world, but there's a lot of hope riding on two studies being conducted in Chicago at Northwestern Medicine’s Cognitive Neurology and Alzheimer's Disease Center. One of them is a clinical trial of a drug that's being called potentially revolutionary. While it may still be years before its efficacy is known, researchers are cautiously optimistic that it could be a turning point in the fight against dementia.
- 01.07.2016 NBC News
Studies that have looked at so-called Super Agers — people who stay cognitively sharp well into old age — have found these people have only one factor in common, says Sandra Weintraub, a professor of neurology, psychiatry and psychology and a neuropsychologist at Northwestern University's Cognitive Neurology and Alzheimer's Disease Center. "Some of them smoke, some of them drink, some of them are couch potatoes, some exercise every day, some eat pork bellies and some consume a Mediterranean diet," Weintraub says. "What they do have in common is that they are very engaged and active. They're so busy it's hard to get them in for research visits."
- 01.05.2016 Crain's Chicago Business
Local biotech researchers should be in line for roughly $50 million more in federal cash this year as a result of some little-noticed tweaks included in the big budget deal that passed Congress a few weeks ago. With the support of robust, sustained federal funding, there is no limit to what science can do to prevent, treat and cure diseases like cancer and Alzheimer's," Durbin said at a news conference at Northwestern University's Feinberg School of Medicine. "After lots of bad news, there's some good news out of Washington.”
Studying patients with a rare form of dementia called primary progressive aphasia has given scientists a new understanding of the way the brain comprehends language.
King Willem-Alexander and Queen Máxima of the Netherlands visited Northwestern University Feinberg School of Medicine on June 3 to announce research collaborations between Northwestern and three Dutch universities, focused on the study of healthy aging.