Study Details
Advancing Research and Treatment for Frontotemporal Lobar Degeneration Frontotemporal Lobar Degeneration (FTLD) is the neuropathological term for a collection of rare neurodegenerative diseases that correspond to four main overlapping clinical syndromes: frontotemporal dementia (FTD), primary progressive aphasia (PPA), corticobasal degeneration syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). The goal of this study is to build a FTLD clinical research consortium to support the development of FTLD therapies for new clinical trials. This study is observational and requires a one-time visit, referred to as the Baseline visit. All ARTFL participants will co-enroll into the Alzheimer's Disease Core Center study. 1. Between 18 and 85 (inclusive) years of age.2. Able to walk (with assistance) at the time of enrollment.3. Have a reliable study partner who can provide an independent evaluation of functioning.4. Speak fluent English.5. Ability to sit for 4-5 hours to undergo cognitive testing, questionnaires, interviews, and a neurological exam.6. Meet the clinical diagnostic criteria for PSP, semantic PPA, CBS, bvFTD, FTD-ALS, or non-fluent PPA. NCT02365922 STU00200202 |