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Eligibility:
The proposed research project must be in some area relevant to understanding Alzheimer's Disease. The
Principal Investigator must hold a faculty or research appointment, or be a postdoctoral fellow at
Northwestern University. Students and residents will not be eligible for these awards.
Amount and Duration:
Pilot grants will typically be limited to one year of support, beginning July 1 and ending June 30 of the
following year. Projects with meritorious progress can apply for a second year of funding. The maximum
level of support will be $28,800 annually. Any one investigator will be eligible only once for pilot project
support unless a convincing case can be made that the proposed pilot project constitutes a significant
departure from the previous pilot project funded through the ADCC. No indirect costs will be provided as
part of the awards. Proposals selected by the internal review committee will be forwarded to the NIA.
Funding is dependent on NIA approval.
It is anticipated that two $28,800 Pilot Research Projects will be funded annually.
Application Deadline:
Applications are due February 29, 2008.. Formal IRB or ACUC approval will be required before projects can begin.
Application Format:
A shortened version of the standard NIH PHS 398 form (Rev. 04/06) should be used and submitted
electronically at the review stage. (Once proposals are chosen for submission to the NIA, both electronic and
hard copy versions are required, including applicable signatures from PI and the Office of Sponsored Research
at Northwestern University. If a new electronic process is required selected applicants will be notified.)
Applications must adhere to all NIH formatting guidelines.
Please include:
1. Face Page (filled out and signed as usual)
2. Abstract Page, (with a brief abstract, performance site and key personnel)
3. Budget for the 12-month pilot project (not in modular budget format).
4. Budget Justification
5. Biographical Sketches (4-page NIH-style for key personnel)
6. Other Support (list current support; specify overlap of the pilot proposal with other
ongoing support, or submitted or planned applications)
7. Resources and Environment (relevant to the Pilot project)
8. Research Plan
Specific Aims (one page maximum)
Background and Significance (three pages maximum)
Research Design and Methods (five pages maximum)
Human Subjects or Vertebrate Animals
Literature Cited (two pages maximum)
**FOR POSTDOCTORAL FELLOWS ONLY: You must also include with your
application a letter from your Mentor supporting the application and confirming
the time and resource commitment. If you are on a visa, proof that your visa
extends through the duration of the project period will be required.
Electronic versions of the form pages can be downloaded at
http://www.research.northwestern.edu/research/osr/forms.html#NIH
Target categories for support:
Junior investigators with an interest in AD, who require
initial support in order to obtain feasibility data for future R01-type applications.
Established investigators in AD research (testing a
new hypothesis or methodology that is not an extension of ongoing research or
is a high-risk new project not currently supported by their current
grant support) Established investigators in non-AD fields (who wish
to bring novel approaches to AD research)
Review Criteria:
1. Significance to the field of AD research
2. Scientific merit and experimental design
3. Use of subjects and/or tissue from the Clinical and/or
Neuropathology
Cores of the Northwestern Alzheimer's Disease Center
4. Appropriateness of proposed research time schedule
5. Appropriateness of proposed budget
6. Probability that the pilot project will lead to independent
funding
Reporting Requirements:
Grantees will be required to summarize their research progress on April 1, 2009. A final research and
expenditures report will be required on October 1, 2009. Pilot grant awardees will be expected to present a
poster summarizing their grant progress during Alzheimer’s Day on May 8, 2008. Investigators should
acknowledge Northwestern Alzheimer's Disease Center support and grant number PHS AG13854 on any
publications resulting from pilot grant support.
Please submit completed applications
in electronic form to:
CNADC-Admin@northwestern.edu
Further information on the Pilot
Grant program can be obtained
from Dr. John Disterhoft at:
Telephone: (312) 503-7982
Fax: (312) 503-2090
E-mail: jdisterhoft@northwestern.edu
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